Which condition can lead to calcium calculi as an indication for Thiazide Diuretics?

Which condition can lead to calcium calculi as an indication for Thiazide Diuretics?

• A. Hypercalcemia
• B. Hyperkalemia
• C. Hypokalemia
• D. Hypocalcemia

Answer: (A)

Thiazide diuretics are particularly effective for preventing the formation of calcium calculi, or kidney stones, that are associated with hypercalcemia. Hypercalcemia refers to an elevated level of calcium in the blood, which can lead to the precipitation of calcium in the kidneys, forming stones. By administering thiazide diuretics, the renal tubular reabsorption of calcium is enhanced, which helps reduce calcium levels in the urine, thereby decreasing the likelihood of stone formation. This mechanism makes thiazide diuretics a first-line treatment for patients at risk for calcium stones. Additionally, they may promote the reabsorption of calcium, counteracting the stone formation. The other conditions listed do not directly relate to the formation of calcium calculi in the same way, making them less relevant in this context.

Thiazide diuretics are particularly effective for preventing the formation of calcium calculi, or kidney stones, that are associated with hypercalcemia. Hypercalcemia refers to an elevated level of calcium in the blood, which can lead to the precipitation of calcium in the kidneys, forming stones. By administering thiazide diuretics, the renal tubular reabsorption of calcium is enhanced, which helps reduce calcium levels in the urine, thereby decreasing the likelihood of stone formation.

This mechanism makes thiazide diuretics a first-line treatment for patients at risk for calcium stones. Additionally, they may promote the reabsorption of calcium, counteracting the stone formation. The other conditions listed do not directly relate to the formation of calcium calculi in the same way, making them less relevant in this context.