What level indicates toxicity for Theophylline according to therapeutic dosage guidelines?

What level indicates toxicity for Theophylline according to therapeutic dosage guidelines?

• A. 15
• B. 20
• C. 25
• D. 30

Answer: (B)

Theophylline is a medication used primarily to treat respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD). It has a narrow therapeutic range, meaning there is a small difference between effective doses and toxic doses. Therapeutic levels of Theophylline typically range from 5 to 15 mcg/mL, with levels above 20 mcg/mL considered to be potentially toxic. This level suggests that the medication is reaching concentrations that could lead to adverse effects and symptoms of toxicity, including nausea, vomiting, tachycardia, and seizures. A therapeutic level of 20 mcg/mL is the threshold at which signs of toxicity may begin to manifest, making this level critical for monitoring in patients receiving Theophylline therapy. Therefore, identifying this level as indicative of toxicity is essential for safe medication administration and patient safety in clinical practice. Continuous monitoring and appropriate adjustments of the medication dosage can help maintain Theophylline levels within a safe therapeutic range to prevent toxicity.

Theophylline is a medication used primarily to treat respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD). It has a narrow therapeutic range, meaning there is a small difference between effective doses and toxic doses.

Therapeutic levels of Theophylline typically range from 5 to 15 mcg/mL, with levels above 20 mcg/mL considered to be potentially toxic. This level suggests that the medication is reaching concentrations that could lead to adverse effects and symptoms of toxicity, including nausea, vomiting, tachycardia, and seizures.

A therapeutic level of 20 mcg/mL is the threshold at which signs of toxicity may begin to manifest, making this level critical for monitoring in patients receiving Theophylline therapy. Therefore, identifying this level as indicative of toxicity is essential for safe medication administration and patient safety in clinical practice. Continuous monitoring and appropriate adjustments of the medication dosage can help maintain Theophylline levels within a safe therapeutic range to prevent toxicity.